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I would do the same thing that is the current accepted practice. I would spend according to the lobbyists wishes for whichever special interest group was putting the most money in my back pocket....just like the corrupt politicians are presently doing. If you want to do the most good with the least amount of money...the only way is to keep the money away from the politicians and turn it over to a scientific advisory panel void from any and all political influence and/or involvement.